Article

A 16p11.2 deletion mouse model displays quantitatively and qualitatively different behaviours in sociability and social novelty over short- and long-term observation

2022-09-30

Abstract excerpt

<h4>Background: </h4> Autism spectrum disorders affect more than one percent of the population, impairing social communication and increasing stereotyped behaviours. A micro-deletion of the 16p11.2 BP4-BP5 chromosomic region has been identified in one percent of patients also displaying intellectual disabilities. In mouse models generated to understand the mechanisms of this deletion, learning and memory deficits...

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Literature Corpus work: 36b5ab15-c2cb-5507-b179-ef485c025d91
DOI: 10.21203/rs.3.rs-2108808/v1

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