Article
Genome-wide analysis of the interplay between chromatin-associated RNA and 3D genome organization in human cells
2021-06-11
Abstract excerpt
The interphase genome is dynamically organized in the nucleus and decorated with chromatin-associated RNA (caRNA). It remains unclear whether the genome architecture modulates the spatial distribution of caRNA and vice versa. Here, we generate a resource of genome-wide RNA-DNA and DNA-DNA contact maps in human cells. These maps reveal the chromosomal domains demarcated by locally transcribed RNA, hereafter termed...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 649fb747-bb9a-54a2-94d1-1fdd83eb05f7
- DOI
- 10.1101/2021.06.10.447969