Article

Multimodal computational framework identifies B cell convergence in autoimmunity and ageing

2026-07-03

Abstract excerpt

Identification of the origin of pathogenic immune cells is crucial for therapeutic interventions and diagnosis but pseudotime methods struggle to trace immune cells accurately. Current trajectory inference methods for B cell development and response in health and disease either ignore or underutilize antigen receptor sequence information, limiting their ability to resolve developmental pathways, particularly for p...

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Literature Corpus work: 26739a62-1b80-5d09-b65a-10b2d4b5f044
DOI: 10.64898/2026.06.29.735110

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