Article

<i>Dandelion</i> utilizes single cell adaptive immune receptor repertoire to explore lymphocyte developmental origins

2022-11-19

Abstract excerpt

Assessment of single-cell gene expression (scRNA-seq) and adaptive immune receptor sequencing (scVDJ-seq) has been invaluable in studying lymphocyte biology. Here, we introduce Dandelion , a computational pipeline for scVDJ-seq analysis. It enables the application of standard V(D)J analysis workflows to single-cell datasets, delivering improved V(D)J contig annotation and the identification of non-productive and...

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Literature Corpus work: a4de8d3c-26c8-54e5-aa58-e9baee8e8e71
DOI: 10.1101/2022.11.18.517068

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