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Berberine Promotes TREM2-Dependent Phagocytosis of Amyloid-β By Microglia

2021-05-26

Abstract excerpt

<h4>Background: </h4> The production and accumulation of amyloid-β (Aβ) is the most important pathological feature of Alzheimer’s Disease (AD), and the deficiency of Aβ clearance contributes to the progression of AD. TREM2-dependent microglial activation may be the key to Aβ clearance. BBR plays the neuroprotective role in the progression of AD by inhibiting Aβ production and promoting Aβ degradation. However, the...

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Literature Corpus work
265f4556-022f-5408-ac08-be8467bd85e5
DOI
10.21203/rs.3.rs-534325/v1
Open publication

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Berberine Promotes TREM2-Dependent Phagocytosis of Amyloid-β By MicrogliaDOI 10.21203/rs.3.rs-534325/v1
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