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Article

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases.

Molecular neurobiology - 1 Mar 2016

Tang Yu, Le Weidong

Abstract excerpt

One of the most striking hallmarks shared by various neurodegenerative diseases, including Parkinson's disease, Alzheimer's disease (AD), and amyotrophic lateral sclerosis, is microglia-mediated neuroinflammation. Increasing evidence indicates that microglial activation in the central nervous system is heterogeneous, which can be categorized into two opposite types: M1 phenotype and M2 phenotype. Depending on the...

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PMID: 25598354
DOI: 10.1007/s12035-014-9070-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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