Article
An overview on microglial origin, distribution, and phenotype in Alzheimer's disease.
Journal of cellular physiology - 1 Jun 2024
Islam Rezwanul, Choudhary Hadi, Rajan Robin, Vrionis Frank, Hanafy Khalid A
Abstract excerpt
Alzheimer's disease (AD) is the most common neurodegenerative disease that is responsible for about one-third of dementia cases worldwide. It is believed that AD is initiated with the deposition of Ab plaques in the brain. Genetic studies have shown that a high number of AD risk genes are expressed by microglia, the resident macrophages of brain. Common mode of action by microglia cells is neuroinflammation and...
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