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Article

Could Polygenic Risk Scores Be Useful in Psychiatry?: A Review.

JAMA psychiatry - 1 Feb 2021

Murray Graham K, Lin Tian, Austin Jehannine, McGrath John J, Hickie Ian B, Wray Naomi R

Abstract excerpt

Importance: Polygenic risk scores (PRS) are predictors of the genetic susceptibility to diseases, calculated for individuals as weighted counts of thousands of risk variants in which the risk variants and their weights have been identified in genome-wide association studies. Polygenic risk scores show promise in aiding clinical decision-making in many areas of medical practice. This review evaluates the potential...

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Source

Identifiers

PMID: 33052393
DOI: 10.1001/jamapsychiatry.2020.3042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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