Article

Rearrangement of 3D genome organization in breast cancer epithelial - mesenchymal transition and metastasis organotropism

2024-08-25

Abstract excerpt

<h4>ABSTRACT</h4> Breast cancer cells exhibit organotropism during metastasis, showing preferential homing to certain organs such as bone, lung, liver, and brain. One potential explanation for this organotropic behavior is that cancer cells gain properties that enable thriving in certain microenvironments. Such specific metastatic traits may arise from gene regulation at the primary tumor site. Spatial genome org...

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Literature Corpus work: 25aeb88e-776a-54e8-bb8d-082e0964043f
DOI: 10.1101/2024.08.23.609227

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