Article

HDAC3 regulates senescence and lineage specificity in non-small cell lung cancer

2020-10-14

Abstract excerpt

<h4>Summary</h4> Transcriptional deregulation is a common feature of many cancers, which is often accompanied by changes in epigenetic controls. These findings have led to the development of therapeutic agents aimed at broad modulation and reprogramming of transcription in a variety of cancers. Histone Deacetylase 3, HDAC3, is one of the main targets of HDAC inhibitors currently in clinical development as cancer...

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Literature Corpus work: 25402da4-59bf-52aa-861c-738483b0d2bf
DOI: 10.1101/2020.10.14.338590

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