Article

Integrative Mapping of Regulatory Variation in African American Hepatocytes Using Colocalization and MPRA: Toward Precision Drug Response

2026-05-20

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Genomic datasets informing pharmacogenomic discovery often underrepresent individuals of African ancestry, limiting understanding of ancestry-specific regulatory variation and its implications for precision medicine. This gap hampers accurate gene regulatory modeling and equitable delivery of precision medicine. <bold>Results:</bold> We generated an express...

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Literature Corpus work: 2517819d-2996-5019-8ab0-da701de3de7b
DOI: 10.21203/rs.3.rs-9611937/v1

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