Article

MeQTL Mapping in African American Hepatocytes Reveals Shared Genetic Regulators of DNA Methylation and Gene Expression

2025-01-26

Abstract excerpt

Methylation quantitative trait loci (meQTL) mapping can provide insight into the genetic architecture underlying the epigenome by identifying single-nucleotide polymorphisms (SNPs) associated with differential methylation at methylation sites (CpGs) across the genome. Given that the epigenetic architecture underlying differences in gene expression can vary across racial populations, performing epigenomic studies i...

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Literature Corpus work: b67cee84-9b6b-5ebd-853d-763f13bd9422
DOI: 10.1101/2025.01.23.634506

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