Back to search

Article

Uncovering the role of admixture in disease and drug response: Association of hepatocyte gene expression and DNA methylation with African Ancestry in African Americans

2018-12-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> African Americans (AAs) are an admixed population with portions of their genome derived from West Africans and Europeans. In AAs, the proportion of West African ancestry (WAA) can vary widely and may explain the genetic drivers of disease, specifically those that disproportionately affect this understudied population. To examine the relationship between the proportion of WAA...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
92a9f895-3c38-5e96-97a8-ff75449513eb
DOI
10.1101/491225
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Uncovering the role of admixture in disease and drug response: Association of hepatocyte gene expression and DNA methylation with African Ancestry in African AmericansDOI 10.1101/491225
Select a neighboring publication to make it the new centre.