Article
Discovery of novel hepatocyte eQTLs in African Americans.
PLoS genetics - 1 Apr 2020
Zhong Yizhen, De Tanima, Alarcon Cristina, Park C Sehwan, Lec Bianca, Perera Minoli A
Abstract excerpt
African Americans (AAs) are disproportionately affected by metabolic diseases and adverse drug events, with limited publicly available genomic and transcriptomic data to advance the knowledge of the molecular underpinnings or genetic associations to these diseases or drug response phenotypes. To fill this gap, we obtained 60 primary hepatocyte cultures from AA liver donors for genome-wide mapping of expression...
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