Article

Characterizing gene expression responses to biomechanical strain in an <i>in vitro</i> model of osteoarthritis

2021-02-22

Abstract excerpt

Osteoarthritis ( OA ) is a common chronic degenerative joint disease affecting articular cartilage and underlying bone. Both genetic and environmental factors appear to contribute to the development of this disease. Specifically, pathological levels of biomechanical stress on joints play a notable role in disease initiation and progression. Population-level gene expression studies of cartilage cells experiencing...

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Literature Corpus work: 24b1d485-fa8a-5e59-ba1e-c7c9982e6a9a
DOI: 10.1101/2021.02.22.432314

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