Article
Characterizing gene expression in an in vitro biomechanical strain model of joint health
2022-09-27
Abstract excerpt
<h4>Background: </h4> Both genetic and environmental factors appear to contribute to joint health and disease. For example, pathological levels of biomechanical stress on joints play a notable role in initiation and progression of osteoarthritis (OA), a common chronic degenerative joint disease affecting articular cartilage and underlying bone. Population-level gene expression studies of cartilage cells experienci...
Topics
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- Cancer-related molecular mechanisms research
- Cell Adhesion Molecules Research
- Circular RNAs in diseases
- Neurobiology and Insect Physiology Research
- Osteoarthritis Treatment and Mechanisms
- RNA Interference and Gene Delivery
- Silk-based biomaterials and applications
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- 7148d9d6-693b-5dc1-a4dd-ec2b9a515849
- DOI
- 10.12688/f1000research.109602.2
