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Understanding the effects of mesenchymal stromal cell therapy for treating osteoarthritis using an <i>in vitro</i> co-culture model

2022-08-26

Abstract excerpt

Osteoarthritis (OA) is a leading cause of chronic pain and disability, for which there is no cure. Mesenchymal stromal cells (MSCs) have been used in clinical trials for treating OA due to their unique functions to send paracrine anti-inflammatory and trophic signals. Interestingly, these studies have shown mainly short-term effects of MSCs in improving pain and joint function, rather than sustained and consistent...

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Literature Corpus work
7ef836d9-effb-583a-96b2-c30c9e0dabf9
DOI
10.1101/2022.08.25.505255
Open publication

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Understanding the effects of mesenchymal stromal cell therapy for treating osteoarthritis using an <i>in vitro</i> co-culture modelDOI 10.1101/2022.08.25.505255
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