A systems biology approach to defining regulatory mechanisms for cartilage and tendon cell phenotypes

Abstract excerpt

Phenotypic plasticity of adult somatic cells has provided emerging avenues for the development of regenerative therapeutics. In musculoskeletal biology the mechanistic regulatory networks of genes governing the phenotypic plasticity of cartilage and tendon cells has not been considered systematically. Additionally, a lack of strategies to effectively reproduce in vitro functional models of cartilage and tendon is...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Knee injuries and reconstruction techniques
• Share to Osteoarthritis Treatment and Mechanisms
• Share to Tendon Structure and Treatment