Article

Identification of clock as a mechanosensitive gene by large-scale DNA microarray analysis: downregulation in osteoarthritic cartilage

2006-06-01

Abstract excerpt

The chondrocytes of cartilage have so far been reported to include three mechanoresponsive genes: cartilage matrix protein (CMP, matrilin-1), type X collagen, and Indian hedgehog (Ihh). In fact, all of the genes identified in these chondrocytes are associated solely with mechanical stress. In this study we examined the how mechanical stress influenced the patterns of gene expression of chondrocytes in three-dimens...

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Literature Corpus work: bcdc94fe-2fd2-55bd-a1f9-b1b8d725db31
DOI: 10.3109/s10165-006-0469-3

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