Article

Cardiac fibroblasts regulate cardiomyocyte hypertrophy through dynamic regulation of type I collagen

2022-05-26

Abstract excerpt

<h4>Rationale</h4> Cardiomyocytes and fibroblasts in the heart communicate through both secreted growth factors as well as through sensing the structural properties of the extracellular matrix that each helps generate. Previous studies have shown that defects in fibroblast activity during disease stimulation result in altered cardiomyocyte hypertrophy, although the role that collagen might play in this communicat...

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Literature Corpus work: 24a9e180-54b1-56ce-9f6c-fe0afce83ef0
DOI: 10.1101/2022.05.25.493406

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