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Cardiac Fibrosis and Fibroblasts

6 Jul 2021

Abstract excerpt

Cardiac fibrosis is the excess deposition of extracellular matrix (ECM), such as collagen. Myofibroblasts are major players in the production of collagen, and are differentiated primarily from resident fibroblasts. Collagen can compensate for the dead cells produced by injury. The appropriate production of collagen is beneficial for preserving the structural integrity of the heart, and protects the heart from...

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PMID: 34359886
DOI: 10.3390/cells10071716

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