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Cardiomyocyte-fibroblast crosstalk in the postnatal heart

3 Apr 2023

Abstract excerpt

During the postnatal period in mammals, the heart undergoes significant remodeling in response to increased circulatory demands. In the days after birth, cardiac cells, including cardiomyocytes and fibroblasts, progressively lose embryonic characteristics concomitant with the loss of the heart's ability to regenerate. Moreover, postnatal cardiomyocytes undergo binucleation and cell cycle arrest with induction of...

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PMID: 37077417
DOI: 10.3389/fcell.2023.1163331

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