Article
Cardiac fibroblast sub-types in vitro reflect pathological cardiac remodeling in vivo
6 Jun 2022
Abstract excerpt
Many heart diseases are associated with fibrosis, but it is unclear whether different types of heart disease correlate with different subtypes of activated fibroblasts and to which extent such diversity is modeled during in vitro activation of primary cardiac fibroblasts. Analyzing the expression of 82 fibrosis related genes in 65 heart failure (HF) patients, we identified a panel of 12 genes clearly...
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