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Tract-specific white matter microstructure alterations among young adult <i>APOE</i> ε4 carriers: A replication and extension study

2022-03-28

Abstract excerpt

The parahippocampal cingulum bundle (PHCB) connects regions known to be vulnerable to early Alzheimer’s disease (AD) pathology, such as posteromedial cortex and medial temporal lobe. While AD-related pathology has been robustly associated with alterations in PHCB microstructure, specifically lower fractional anisotropy (FA) and higher mean diffusivity (MD), emerging evidence indicates that the reverse pattern is e...

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Identifiers and source

Literature Corpus work
24952212-a2c1-5aa4-a2b0-95c1ce218779
DOI
10.1101/2022.03.23.485532
Open publication

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Tract-specific white matter microstructure alterations among young adult <i>APOE</i> ε4 carriers: A replication and extension studyDOI 10.1101/2022.03.23.485532
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