Article
The APOE ε4 allele in relation to brain white-matter microstructure in adulthood and aging.
Scandinavian journal of psychology - 1 Jun 2014
Nyberg Lars, Salami Alireza
Abstract excerpt
The Apolipoprotein E (ApoE) ε4 allele is a major genetic risk factor for sporadic Alzheimer's disease and has been associated with structural and functional brain alterations across the adult life span. Recent studies have presented evidence that ε4 affects microstructural properties of brain white matter (WM) in non-demented carriers of the ε4 allele, but conflicting evidence has been presented as well. The main...
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