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Amyloid, Tau, and APOE in Alzheimer's Disease: Impact on White Matter Tracts.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2025

Chandio Bramsh Qamar, Villalon-Reina Julio E, Nir Talia M, Thomopoulos Sophia I, Feng Yixue, Benavidez Sebastian, Jahanshad Neda, Harezlak Jaroslaw, Garyfallidis Eleftherios, Thompson Paul M

Abstract excerpt

Alzheimer's disease (AD) is characterized by cognitive decline and memory loss due to the abnormal accumulation of amyloid-beta (Aβ) plaques and tau tangles in the brain; its onset and progression also depend on genetic factors such as the apolipoprotein E (APOE) genotype. Understanding how these factors affect the brain's neural pathways is important for early diagnostics and interventions. Tractometry is an...

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PMID: 39670385

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