Article

Mapping the impact of age and APOE risk factors for late onset Alzheimer’s disease on long range brain connections through multiscale bundle analysis

2024-06-28

Abstract excerpt

Alzheimer’s disease currently has no cure and is usually detected too late for interventions to be effective. In this study we have focused on cognitively normal subjects to study the impact of risk factors on their long-range brain connections. To detect vulnerable connections, we devised a multiscale, hierarchical method for spatial clustering of the whole brain tractogram and examined the impact of age and APOE...

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Literature Corpus work: d042f290-90c7-5573-9a32-151697335243
DOI: 10.1101/2024.06.24.599407

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