Article

Amyloid, Tau, and APOE in Alzheimer’s Disease: Impact on White Matter Tracts

2024-08-05

Abstract excerpt

Alzheimer’s disease (AD) is characterized by cognitive decline and memory loss due to the abnormal accumulation of amyloid-beta (A β ) plaques and tau tangles in the brain; its onset and progression also depend on genetic factors such as the apolipoprotein E (APOE) genotype. Understanding how these factors affect the brain’s neural pathways is important for early diagnostics and interventions. Tractometry is an a...

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Literature Corpus work: 4e6ecaea-d3f8-5858-a9dd-a446fc3363b3
DOI: 10.1101/2024.08.05.606560

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