Article

Fibroblastic reticular cells provide a supportive niche for lymph node-resident macrophages

2021-11-24

Abstract excerpt

<h4>Summary</h4> The lymph node (LN) is home to resident macrophage populations that are essential for immune function and homeostasis. The T cell paracortical zone is a major site of macrophage efferocytosis of apoptotic cells, but key factors controlling this niche are undefined. Here we show that fibroblastic reticular cells (FRCs) are an essential component of the LN macrophage niche. Macrophages co-localised...

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Identifiers and source

Literature Corpus work: 2486a67f-d657-564a-9878-7eb777dad135
DOI: 10.1101/2021.11.24.469855

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