Back to search

Article

Spatial transcriptomics resolves ductal <i>TREM2</i> <sup>+</sup> and stromal <i>FOLR2</i> <sup>+</sup> macrophages in the normal human breast at microanatomical resolution

2026-08-06

Abstract excerpt

Macrophage identities are coupled to specialized roles through their local niches of residence. In the breast, macrophages contribute to epithelial development and re-modeling, immune surveillance, and angiogenesis. These diverse functions imply a spatial organization of distinct transcriptional states. Yet, how this heterogeneity is spatially arranged in the normal human breast at microanatomical resolution remai...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0e2e5a04-4855-54f9-9141-3022670a3ea0
DOI
10.64898/2026.08.05.742266
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Spatial transcriptomics resolves ductal <i>TREM2</i> <sup>+</sup> and stromal <i>FOLR2</i> <sup>+</sup> macrophages in the normal human breast at microanatomical resolutionDOI 10.64898/2026.08.05.742266
Deciphering the spatial landscape and plasticity of immunosuppressive fibroblasts in breast cancerSemantic proximity
A spatially resolved single cell genomic atlas of the adult human breastSemantic proximity
A spatial map of human macrophage niches reveals context-dependent macrophage functions in colon and breast cancer.Semantic proximity
Cell non-autonomous interactions during non-immune stromal progression in the breast tumor microenvironmentSemantic proximity
Analysis of intratumoral immune heterogeneity reveals spatial organisation of immunosuppression in breast cancerSemantic proximity
Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial LocalizationSemantic proximity
Defining and targeting macrophage heterogeneity in the mammary gland and breast cancerSemantic proximity
TREM2+ macrophages regulate suppressive tumor microenvironment in TNBCSemantic proximity
Spatially-Resolved Transcriptomics Define Clinically Relevant Subsets of Macrophages in Diffuse Large B-cell LymphomaSemantic proximity
High-definition spatial transcriptomic profiling of immune cell populations in colorectal cancerSemantic proximity
Single-cell Atlas reveals core function of CPVL/MSR1 expressing macrophages in the prognosis of triple-negative breast cancerSemantic proximity
Spatial Deconvolution of HER2-positive Breast Tumors Reveals Novel Intercellular RelationshipsSemantic proximity
Select a neighboring publication to make it the new centre.