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Follicular Bcl6 reactivity is associated with a unique immune landscape and spatial transcriptome in COVID-19

2024-11-08

Abstract excerpt

<h4>ABSTRACT</h4> The regulation of follicular (F) and germinal center (GC) immune reactivity in human lymph nodes (LNs), particularly during the early stages of viral infections, remains poorly understood. We have analyzed lung-draining lymph nodes (LD-LNs) from COVID-19 autopsies using multiplex imaging and spatial transcriptomics to examine the immune landscape and with respect to the aging. We identified thre...

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Literature Corpus work
ba83bc5b-a5b9-5127-bfd2-044ba3203316
DOI
10.1101/2024.11.07.622471
Open publication

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Follicular Bcl6 reactivity is associated with a unique immune landscape and spatial transcriptome in COVID-19DOI 10.1101/2024.11.07.622471
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