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Article

Characterization of human fibroblastic reticular cells as potential immunotherapeutic tools.

Cytotherapy - 1 May 2017

Valencia Jaris, Jiménez Eva, Martínez Víctor G, Del Amo Beatriz G, Hidalgo Laura, Entrena Ana, Fernández-Sevilla Lidia M, Del Río Francisco, Varas Alberto, Vicente Ángeles, Sacedón Rosa

Abstract excerpt

Fibroblastic reticular cells (FRCs) are essential players during adaptive immune responses not only as a structural support for the encounter of antigen-presenting cells and naive T lymphocytes but also as a source of modulatory signals. However, little is known about this cell population in humans. To address the phenotypical and functional analysis of human FRCs here we established splenic (SP) and mesenteric...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28262465
DOI: 10.1016/j.jcyt.2017.01.010

Genes

BMP4
CCL2
CXCL12
NOS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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