Article

Repurposing the CRISPR-Cas9 System for Targeted Chromatin O-linked β-N-acetylglucosamine Editing

2022-10-27

Abstract excerpt

Eukaryotic gene transcription is controlled by many proteins, including the basal transcription machinery, epigenetic chromatin remodeling complexes, and transcription cofactors. Chromatin and genome-mapping consortia identified O -linked β- N -acetylglucosamine (O-GlcNAc) as an abundant chromatin post-translational modification involved in numerous transcriptional processes, including RNA polymerase function, e...

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Literature Corpus work: 23b6acf2-6acd-5058-b2f7-99be5515277f
DOI: 10.1101/2022.10.27.514044

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Repurposing the CRISPR-Cas9 System for Targeted Chromatin O-linked β-N-acetylglucosamine EditingDOI 10.1101/2022.10.27.514044Read

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