Article

Disruption of gastric mucous granule exocytosis by Helicobacter pylori virulence factor CagA

2021-01-16

Abstract excerpt

<title>Abstract</title> <p><italic>Helicobacter pylori</italic> infection is the strongest known risk factor of stomach cancer. Strains harboring the virulence factor CagA (cytotoxin-associated gene A) significantly stimulate host inflammatory response, which increases the risk of ulceration and cancer. However, the mechanisms by which CagA triggers prolonged inflammation with mucosal damage remain elusive. Based...

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Literature Corpus work: 23ad7913-18a9-547c-a98e-868209c923c0
DOI: 10.21203/rs.3.rs-139758/v1

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