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Roles of the components of the cag -pathogenicity island encoded type IV secretion system in Helicobacter pylori

22 Aug 2024

Abstract excerpt

The Helicobacter pylori (H. pylori) cytotoxin-associated gene pathogenicity island (cagPAI) encodes 31 genes that assemble the cag type IV secretion system (T4SS) apparatus, which includes structures such as the outer membrane core complex, periplasmic ring, inner membrane complex and bacterial hairs. These proteins interact with each other to inject CagA into the host gastric epithelium. There are also...

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PMID: 39171625
DOI: 10.1080/17460913.2024.2383514

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