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Article

Role of type IV secretion in<i>Helicobacter pylori</i>pathogenesis

9 Apr 2008

Abstract excerpt

Helicobacter pylori is a highly successful human-specific gastric pathogen that colonizes more than half the world's population. Infection with this bacterium can induce gastric pathologies ranging from chronic gastritis to peptic ulcers and even cancer. Virulent H. pylori isolates harbour the cag (cytotoxin-associated genes) pathogenicity island, a 40 kb stretch of DNA that encodes components of a type IV...

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PMID: 18410539
DOI: 10.1111/j.1462-5822.2008.01156.x

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