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Article

Role of the cag ‐pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis

1 Feb 2011

Abstract excerpt

Helicobacter pylori is a very successful human-specific bacterium worldwide. Infections of the stomach with this pathogen can induce pathologies, including chronic gastritis, peptic ulcers and even gastric cancer. Highly virulent H. pylori strains encode the cytotoxin-associated gene (cag)-pathogenicity island, which expresses a type IV secretion system (T4SS). This T4SS forms a syringe-like pilus structure for...

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PMID: 21352489
DOI: 10.1111/j.1742-4658.2011.08035.x

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