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Article

Pathogenic mechanisms of the oncoprotein CagA in H. pylori-induced gastric cancer

4 Oct 2016

Abstract excerpt

Infection with Helicobacter pylori is the strongest risk factor for the development of chronic gastritis, gastric ulcer and gastric carcinoma. The majority of the H. pylori-infected population remains asymptomatic, and only 1% of individuals may progress to gastric cancer. The clinical outcomes caused by H. pylori infection are considered to be associated with bacterial virulence, genetic polymorphism of hosts as...

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PMID: 27748858
DOI: 10.3892/or.2016.5145

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