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Tertiary lymphoid structures in cancer

6 Jan 2022

Abstract excerpt

Ectopic lymphoid aggregates, termed tertiary lymphoid structures (TLSs), are formed in numerous cancer types, and, with few exceptions, their presence is associated with superior prognosis and response to immunotherapy. In spite of their presumed importance, the triggers that lead to TLS formation in cancer tissue and the contribution of these structures to intratumoral immune responses remain incompletely...

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PMID: 34990248
DOI: 10.1126/science.abf9419

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