Article

Canonical Pathways Rewiring in Alzheimer’s Disease

2026-04-17

Abstract excerpt

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by the simultaneous disruption of interconnected molecular pathways, yet the structural mechanisms underlying this transcriptional disintegration remain poorly characterized. To address this, we constructed condition-specific gene co-expression networks from DLPFC bulk RNA-seq data, using a mutual information framework with...

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Literature Corpus work: 233ec2c7-3487-51ea-a352-17b6b875d9ad
DOI: 10.20944/preprints202604.1194.v1

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