Article

An Integrative Network-based Analysis Reveals Gene Networks, Biological Mechanisms, and Novel Drug Targets in Alzheimer’s Disease

2019-11-24

Abstract excerpt

Alzheimer’s disease is a highly heritable and severe neuropsychiatric condition. Genome-wide association studies have identified multiple genetic risk factors underlying susceptibility to Alzheimer’s disease, however their functional impact remains poorly understood. To overcome this shortcoming, we integrated genome-wide association summary statistics (71,880 cases, 338,378 controls) with tissue-specific gene co-...

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Literature Corpus work: d2c7ceac-c544-5d1f-9348-ab755beec032
DOI: 10.1101/853580

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