Article

Alzheimer’s disease rewires gene coexpression networks coupling different brain regions

2022-05-24

Abstract excerpt

Connectome studies have revealed how neurodegenerative diseases like Alzheimer’s disease (AD) disrupt functional and structural connectivity among brain regions, but the molecular basis of such disruptions is less studied, with most genomic studies focusing on within-brain-region molecular analyses. We performed an inter-brain-region differential correlation (DC) analysis of postmortem human brain RNA-seq data ava...

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Literature Corpus work: 0b8ffb82-51a2-5593-ae56-4b9764465b70
DOI: 10.1101/2022.05.22.492888

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