Article

Systematic Analysis of Biological Processes Reveals Gene Co-expression Modules Driving Pathway Dysregulation in Alzheimer’s Disease

2024-03-17

Abstract excerpt

Alzheimer’s disease (AD) manifests as a complex systems pathology with intricate interplay among various genes and biological processes. Traditional differential gene expression (DEG) analysis, while commonly employed to characterize AD-driven perturbations, does not sufficiently capture the full spectrum of underlying biological processes. Utilizing single-nucleus RNA-sequencing data from postmortem brain samples...

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Literature Corpus work: 050958f3-cd1e-5102-bb60-8cd37b293ac0
DOI: 10.1101/2024.03.15.585267

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