Article

Long-term dietary interventions fail to mitigate functional connectivity loss and cognitive decline in the TgF344-AD rat model of Alzheimer’s Disease

2025-08-29

Abstract excerpt

<h4>Introduction</h4> Alzheimer’s disease (AD) is a complex neurodegenerative disorder, characterized by altered brain functional connectivity and network activity, detectable using resting-state functional MRI (rsfMRI). Caloric restriction (CR) and its mimetic resveratrol (Rsv) have shown potential in reducing AD-related pathology and preserving brain function, though research on long-term efficacy is limited. T...

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Literature Corpus work: 230ff55b-6e1e-527c-a4e9-ab56a4cc4dcb
DOI: 10.1101/2025.08.25.672063

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