Article

Tau-Connectome Subtypes and Solanezumab Response in Preclinical Alzheimer’s Disease

2025-09-15

Abstract excerpt

<h4>Importance</h4> This study identifies clinically meaningful subtypes within preclinical Alzheimer’s disease (AD) using the functional connectome and introduces tau-predictive functional connectivity as a new tool to stratify risk and treatment response. <h4>Objective</h4> To determine whether fMRI–derived functional connectivity can identify subgroups with differential cognitive outcomes and treatment respon...

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Literature Corpus work: 84dfa8af-950b-5802-acce-c5b479acdeb6
DOI: 10.1101/2025.09.13.25335690

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