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Identification of non-synonymous SNPs Impacting Structure and Function of MLH1 and NBN Proteins: A computational approach.

2025-03-27

Abstract excerpt

<title>Abstract</title> <p>The genes NBN and MLH1 are critical for DNA repair, and this study aimed to detect and predict the effects of pathogenic single nucleotide polymorphisms (SNPs) in their mRNA and protein sequences. An in silico analysis assessed the impact of SNPs on the physicochemical properties, structure, stability, and function of MLH1 and NBN proteins. Results revealed that some SNPs significantly...

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Literature Corpus work
22f4dca3-6adf-5db4-b4ed-6f96dfcf4e78
DOI
10.21203/rs.3.rs-5621917/v1
Open publication

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Identification of non-synonymous SNPs Impacting Structure and Function of MLH1 and NBN Proteins: A computational approach.DOI 10.21203/rs.3.rs-5621917/v1
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