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Article

Functional and structural analysis of non-synonymous single nucleotide polymorphisms (nsSNPs) in the MYB oncoproteins associated with human cancer.

Scientific reports - 17 Dec 2021

Lim Shu Wen, Tan Kennet JunKai, Azuraidi Osman Mohd, Sathiya Maran, Lim Ee Chen, Lai Kok Song, Yap Wai-Sum, Afizan Nik Abd Rahman Nik Mohd

Abstract excerpt

MYB proteins are highly conserved DNA-binding domains (DBD) and mutations in MYB oncoproteins have been reported to cause aberrant and augmented cancer progression. Identification of MYB molecular biomarkers predictive of cancer progression can be used for improving cancer management. To address this, a biomarker discovery pipeline was employed in investigating deleterious non-synonymous single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34921182
DOI: 10.1038/s41598-021-03624-x
PMCID: PMC8683427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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