Article

3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity

2023-08-31

Abstract excerpt

<h4>ABSTRACT</h4> The prevalence of childhood obesity is increasing worldwide, along with the associated common comorbidities of type 2 diabetes and cardiovascular disease in later life. Motivated by evidence for a strong genetic component, our prior genome-wide association study (GWAS) efforts for childhood obesity revealed 19 independent signals for the trait; however, the mechanism of action of these loci rema...

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Literature Corpus work: 22cbd0e7-9f34-5670-8b5b-ff767f898890
DOI: 10.1101/2023.08.30.23294092

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