Article
Strategies to identify causal common genetic variants and corresponding effector genes for paediatric obesity.
Pediatric obesity - 1 Dec 2022
Littleton Sheridan H, Grant Struan F A
Abstract excerpt
BACKGROUND: Childhood obesity rates are on the rise, but there are currently no effective therapies available to slow or halt their progression. Although environmental and lifestyle factors have been implicated in its pathogenesis, childhood obesity is considered a complex disorder with a clear genetic component. Intense genome-wide association study (GWAS) efforts through large-scale collaborations have enabled...
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