The role of common and rare genetic variation on adiposity across childhood.

Abstract excerpt

<title>Abstract</title> <p>Our understanding of the genetic architecture of obesity has primarily been shaped by observations from adult populations with relatively few studies on childhood obesity. To address this gap, we conduct a longitudinal genetic association study in up to ~600,000 individuals with objectively measured or recalled childhood adiposity-related traits. We identify 624 common variant signals (...

Topics

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• Adolescent
• Body Mass Index
• Child
• Genome-Wide Association Study
• Genotype
• Overweight
• Pediatric Obesity
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

ece7e7fb-0625-5b12-85da-e16321aabcb9

DOI

10.21203/rs.3.rs-6649447/v1